Behind the headlines: Study shows there is still no evidence that Alzheimer’s disease is contagious

You may have seen recent headlines claiming that Alzheimer’s disease can be caused by surgical procedures. At Alzheimer’s Society, we want to stop misleading news articles like this and make sure supporters know the truth behind the headlines.

Ruby Ali-Strayton, Research Network volunteer said: 'These misinformed headlines are both ignorant and sensationalist. When I became aware of them it made me angry. Headlines and daft stories are the staple of some newspapers – I know, I used to work on them – and health stories are often served up without any proper thought or research.'

Our research team at Alzheimer’s Society took a look at the evidence to bring you the real story. Alzheimer’s is not a contagious disease, but caused by diseases of the brain from a complex mix of our genes and environment.

What did the research show?

The researchers found a toxic form of the amyloid protein, a key hallmark of Alzheimer’s disease, could be transferred between people in very specific situations. 

Researchers at University College London looked at a rare type of surgery. This involved infusing growth hormone into people who aren’t able to produce enough. Today a synthetic hormone is used, but in the past it was taken from people who had died. Most importantly, this procedure has been phased out for over 35 years.

The study found that the infusion contained the toxic form of amyloid. A small number of people who had this surgery in the 1970's showed build-up of amyloid protein in their blood vessels. This resulted in damage to the surrounding brain tissue – a condition known as cerebral amyloid angiopathy. However they did not have Alzheimer’s disease.

The researchers also showed evidence that this transmissible form of amyloid could cause similar effects in the brains mice. Although not in all the models of mice tested. It’s also important to remember – what is true in mice might not be true in humans!

What do these results mean?

The researchers and other experts emphasise that this does not suggest that Alzheimer’s disease is contagious. Nor that the people studied or the mice developed Alzheimer’s disease. However the researchers do argue that the people affected may have gone on to develop Alzheimer’s with time.

We still don’t know enough about how amyloid protein might be transmitted between people to be certain about any risk. Current surgical methods are strict in their cleaning and disposal of all tools that could become contaminated. 

Further research is needed to be sure whether this is enough. All surgical interventions come with risks; at present the risk of transmission of Alzheimer’s disease seems to be a very low.

Our helpline advisers are here for you.

Our Head of Research at Alzheimer’s Society, Dr James Pickett, clarified the study findings. 

'We’ve known for a long time that amyloid protein is involved in Alzheimer’s disease, but it is just one component. Although researchers found that some of the people who received this procedure had changes in their brain related to the amyloid protein, they didn’t have Alzheimer’s disease itself. The procedure in this study was phased out over 35 years ago, and more modern approaches do not have the same risk of exposure. 

'There remains absolutely no evidence that Alzheimer’s disease is contagious. There are no examples of Alzheimer’s being transmitted from person to person via any current surgical procedures. And there is good evidence to show that blood transfusions don’t increase your chances of developing Alzheimer’s disease.'

What should I do about it?

The researchers in the study, and other experts in surgery and dementia, were quick to reassure that any risk of amyloid being transferred between people is very small.

Professor Bart de Strooper, Director of the Alzheimer’s Society co-founded UK Dementia Research Institute said:

'There is absolutely no reason to postpone or decline brain surgery based on the current evidence'

He also noted that large population studies of almost 1.5 million people in Sweden and Denmark found no evidence that blood transfusions could increase the risk of developing dementia.

What will happen now?

Researchers will continue to investigate if there is any risk that amyloid proteins could be transferred between people. Even if the risk is small, it is important to check we are doing all we can to avoid harm. We would expect this new research to tell us whether there are any other steps that we might need to take to be sure.

Dementia and Alzheimer’s disease are not contagious. They are caused by diseases of the brain, but we can’t catch them from other people. We do know though that there are things we can all do to reduce our risk of developing dementia, like eating a healthy balanced diet, staying active and stopping smoking.

If you are worried about your memory or changes to your thinking skills contact your GP.

How to reduce your risk of dementia

Although getting older is the biggest risk factor for dementia, evidence shows there are things you can do to help reduce your own risk. These include keeping active, eating healthily and exercising your mind.

Find out more
Think this page could be useful to someone? Share it:


Add your own

The words from your expert ex journalist researcher ie: Good evidence and low risk hardly inspire confidence against the argument of Alzheimer’s being contagious or transmitted through surgery or blood transfusions.
As a journalist I’m sure she would be appalled and frustrated if she read an article from a highly respected institute and the response was to rubbish it by saying there is a good chance it isn’t true or the risk is low.

Hi Alan, thanks for getting in touch. This research was carried out by a research team based at a respected university and published in one of the most reputable scientific journals.

The research itself is good quality however we do believe that the way it was reported in the press by some news outlets was misleading, particularly the headlines. This blog aimed to explain the research and put it into perspective so that anyone reading the headlines would have the full picture.

Leave a comment

Your email address will not be published. Required fields are marked with *

The content of this field is kept private and will not be shown publicly.