Scientists investigate the cause of age related memory decline

Researchers at the University of Alabama found that in aged mice models specific changes to cells in the central nervous system could be linked to disruption of brain activity that is necessary for stabilising long term memory.

Alzheimer's Society comment

'This is an exciting new finding that might provide important insights for the development of new treatments to maintain memory in later life.

'A lot more work is needed to see how this links to later life diseases such as Alzheimer's disease and how this relates to changes in the memory of humans. One in three people will die with dementia yet dementia research is desperately under-funded. We must invest more if we are to move forward in our understanding and treatment of this devastating condition.'

Professor Clive Ballard
Director of Research
Alzheimer's Society

Research ref: Shahaf Peleg, University of Alabama, 'Altered Histone Acetylation Is Associated with Age-Dependent Memory Impairment in Mice'.

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Notes to editors:

• One in three people over 65 will die with dementia
• Alzheimer's Society research shows that 750,000 people in the UK have a form of dementia, more than half have Alzheimer's disease. In just 15 years a million people will be living with dementia. This will soar to 1.7 million people by 2051.
• Alzheimer's Society champions the rights of people living with dementia and the millions of people who care for them.
• Alzheimer's Society works in England, Wales and Northern Ireland
• Alzheimer's Society supports people to live well with dementia today and funds research to find a cure for tomorrow. We rely on voluntary donations to continue our vital work. You can donate now by calling 0845 306 0898 or visiting alzheimers.org.uk
• Alzheimer's Society provides a National Dementia Helpline, the number is 0845 300 0336 or visit alzheimers.org.uk

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