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HIV-related memory loss linked to Alzheimer's protein

Published 8 December 2009

New research published in Neurology today suggests that amyloid, one of the proteins associated with Alzheimer’s disease, may also play a role in the memory loss of people with HIV.

Researchers examined cerebrospinal fluid (CSF) and found that the amount of amyloid was lower in Alzheimer's patients and HIV patients with memory problems, when compared to HIV patients without memory problems and healthy people. The other protein associated with Alzheimer's, Tau, was unchanged. Lower amounts of amyloid in the CSF suggest that amyloid processing in the brain is also affected.

 

 

'Alzheimer's like symptoms experienced by people with HIV can be frightening and confusing but this research builds on our understanding of why these symptoms occur and may help people get a more accurate diagnosis. 

 

'Using spinal fluid techniques to diagnose dementia adds great value to research yet the UK lags far behind other countries who routinely use them. We must invest more in dementia research and increase the use of spinal fluid techniques if the UK is to lead the fight against dementia.'

 

 

Dr Susanne Sorensen
Head of Research
Alzheimer's Society

Notes to editors

 

  • One in three people over 65 will die with dementia
  • Alzheimer's Society research shows that 700,000 people in the UK have a form of dementia, more than half have Alzheimer's disease. In less than 20 years nearly a million people will be living with dementia. This will soar to 1.7 million people by 2051.
  • Alzheimer's Society champions the rights of people living with dementia and the millions of people who care for them.
  • Alzheimer's Society works in England, Wales and Northern Ireland
  • Alzheimer's Society needs to raise money to help people live well with dementia today and for research to find a cure for tomorrow. You can donate now by calling 0845 306 0898 or visiting alzheimers.org.uk
  • Alzheimer's Society provides a National Dementia Helpline, the number is 0845 300 0336 or visit alzheimers.org.uk