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Tests could help predict Alzheimer's disease progression

Published 1 July 2010

Specific brain scans and memory tests could indicate whether people with mild cognitive impairment (MCI) will go on to develop Alzheimer’s disease, according to new research.

The study published online by Neurology on Wednesday 30 June 2010,  found people who showed abnormal results on a PET brain scan which detects metabolic abnormalities and episodic memory tests were nearly 12 times more likely to develop Alzheimer's disease.

Alzheimer's Society comment:

'We don't currently know which people with MCI will go on to develop Alzheimer's disease. This important study moves us a step closer to unravelling this mystery. The tests identified could have real benefits in our search for a cause or cure for the disease, helping researchers identify suitable participants for drug trials.

At this stage it is a leap too far to say these tests can have immediate benefits for routine diagnosis. They are currently too expensive and the prognosis of Alzheimer's they provide is not 100 per cent guaranteed. We need more investment into research and treatment if we are to move our knowledge forward and improve the lives of people with dementia.'


Dr Susanne Sorensen
Head of Research
Alzheimer's Society