Mapping differences in mental abilities in people with and without dementia

Lead Investigator: Dr Graciela Muniz-Terrera
Institution: University of Cambridge
Grant type: Research Fellowship
Duration: 3 years
Amount: 135,876
Scientific title: Evidence synthesis of trajectories of cognitive change due to chronological age, death and preclinical dementia.

What do we already know?

Various mental abilities can be tested, and the results analysed to show cognitive ability - the ability to process, retain and use information. Some studies have investigated the rate of decline as people get older, but there is no single forecast for cognitive decline, as these studies all used slightly different techniques for measurements.

We know that there are different ways that cognitive ability can be analysed, with many different factors making up the whole picture, and that many different factors need to be investigated to find clearer answers.

What does this project involve?

This study will combine the data from many different studies to produce analyses of data across different countries. The research aims to use new techniques to forecast how mental ability declines in people with and without dementia. These will take into account separate aspects of cognitive ability, and different factors which may affect cognitive decline.

How will this benefit people with dementia?

Taking into account lots of different factors when analysing data will give a much clearer picture, showing us what is 'normal' ageing and what may be due to dementia or other things. Understanding what is 'normal' ageing with regards to cognitive ability, and what may be predictors of illness, is important in the early diagnosis and treatment of dementia.